Microbiota shaping and bioburden monitoring of indoor antimicrobial surfaces

Indoor residents are constantly exposed to dynamic microbiota that have significant health effects. In addition hand hygiene, cleaning, and disinfection, antimicrobial coatings (AMCs) can prevent the spread of infectious diseases in public areas. The sustainable use antimicrobial-coated products requires an assessment their pros cons for human environment. toxicity resistance risks AMCs been considered, but large-scale genetic studies on microbial community compositions resistomes scarce. AMC reduce total number microbes a surface poses risk dysbiosis, imbalance, such as polarized growth metallophilic, metal- antimicrobial-resistant, other survivor bacteria, overall reduction diversity. Loss diversity may lead enrichment harmful bacteria increased communicable or immunological non-communicable inflammatory (NCDs). buildings, kindergartens nursing homes elderly, is likely increase due epidemics pandemics recent years. Therefore, comprehensive metagenomic research needed monitor effects indoor functions. Although determination good homeostasis difficult, communities health-protective should be identified using sequencing approach before implementation AMCs.